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Senior Scientist/Principle Scientist– Cell Biology and Immunology

Legendbiotech · Piscataway, NJ, United States

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Role Overview:
Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking talented and motivated individuals to join the group of Cell Biology and Immunology in the R&D Department located at Piscataway of New Jersey. The successful candidate should possess extensive knowledge and hands-on experience in oncology, cell biology and immunology, in particular TCR-T/CAR-T cell biology. The candidate will be able to contribute to the effort for developing T cell therapy platform, building and optimizing cell-based immunoassays to characterize and assess TCR-T/CAR-T cell functions. Experience with TCR-T/CAR-T cells is preferred. As major contributors of pipeline development, the candidates need to demonstrate the ability of planning, designing, executing complicated experiments and delivering scientific results in a cross-functional environment. This position also requires supervision and management skills.
Major Responsibilities: 

• Independently plan, design, execute experiments to assess the in-vitro functions of TCR-T/CAR-T cells
• Develop T cell therapy platform and optimize cell-based immunoassays, including ex-vivo antigen-specific T cell isolation and expansion. Multi-color flow cytometry, ELISA, ELISPOT, cytotoxic assays
• Deliver scientific results at internal and external meetings
• Supervise associate scientists for routine laboratory work
• Help group leader for general laboratory management
• Serve as the major contributors for pipeline development

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