Associate Research Scientist II

Role Overview:
Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking a talented and motivated candidate to join the R&D cell biology and immunology lab at US site. The successful candidate will contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies.  The successful candidate will have a strong Molecular biology/Cell biology and Immunology background, and expect to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.
Major Responsibilities:  

• Assist in developing T cell therapy platform, perform cell-based immunoassays, including ex-vivio antigen specific T cell isolation and expansion, Viral-vector based introduction ofTCRs / CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays
• Culture and characterize genetically modified human T cells and tumor cells including gene expression and cell functionalities testing
• Plan and execute in vitro functional assays with T cells according to project goals and timelines.
• Effectively communicate plans and results in both oral and written form.
• Ability to work in a highly dynamic collaborative team environment.
• Other duties as assigned